LE-580FX software does not run without connecting LE-580FX device into a PC.
On the other hand, Wireshark can display data measured by LE-580FX software without connecting LE-580FX device into a PC.

Also, uses can use the advanced protocol translation functions (several hundred of kinds) on Wireshark.

Wireshark can capture data using LE-580FX device to use the advanced capture capability on Wireshark.

LE-580FX software have accurate packet counter function and time stamp.
Users can select LE-580FX software or Wireshark to suit each purpose of measuring.